Product Name :
Patched Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
A230106A15Rik antibody BCNS antibody FLJ26746 antibody FLJ42602 antibody Holoprosencephaly 7 antibody HPE7 antibody mes antibody NBCCS antibody OTTHUMP00000021709 antibody OTTHUMP00000021710 antibody 展开
Function :
This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
The antiserum was produced against synthesized peptide derived from human Patched. AA range:1-50
Species reactivity:
Human, Mouse
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.5-Bromo-1H-pyrazole-3-carboxylic acid Data Sheet Aliquot store at -20℃ or -80℃.4-(4-Bromophenyl)-1-methyl-1H-pyrazole Data Sheet Avoid repeated freeze / thaw cycles.PMID:33723798
Storage buffer solution:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
160 kDa
Positive control :
Brain, Cerebellum, Fetal brain, Lung.