Product Name :
Phospho-p38 alpha / MAPK14 (T180) Recombinant Rabbit Monoclonal Antibody [PSH06-25]
Predicted band size :
41 kDa
Observed band size :
38 kDa
Synonyms:
CSAID Binding Protein 1 antibody CSAID binding protein antibody CSAID-binding protein antibody Csaids binding protein antibody CSBP 1 antibody CSBP 2 antibody CSBP antibody CSBP1 antibody CSBP2 antibody CSPB1 antibody 展开
Function :
MAP (mitogen-activated protein) kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. p38α, p38β and p38γ, also known as MAPK14, MAPK11 and MAPK12, respectively, each contain one protein kinase domain and belong to the MAP kinase family. Expressed in different areas throughout the body with common expression patterns in heart, p38 proteins use magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins.CataCXium A Pd G3 Formula Via their catalytic activity, p38α, p38β and p38γ are involved in a variety of events throughout the cell, including signal transduction pathways, cytokine production and cell proliferation and differentiation. The p38 proteins are subject to phosphoryation on Thr and Tyr residues, an event which is thought to activate the phosphorylated protein.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic phosphopeptide corresponding to residues surrounding Thr180 of human p38 alpha / MAPK14.Formula of tert-Butyl 9-bromononanoate
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P, IF-Cell, FC
Coupling :
unconjugated
Clone number:
PSH06-25
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33417700 Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 41 kDa
Positive control :
Jurkat cell lysate, Jurkat treated with UV for 1 hour cell lysate, NIH/3T3 treated with 25μg/mL Anisomycin for 30 minutes cell lysate, C6 treated with 25μg/mL Anisomycin for 30 minutes cell lysate, mouse colon tissue, rat colon tissue, NIH/3T3 cells treated with 25μg/mL Anisomycin for 30 minutes.