Product Name :
Syk Recombinant Rabbit Monoclonal Antibody [PSH0-76]
Predicted band size :
72 kDa
Observed band size :
70 kDa
Synonyms:
EC 2.7.10.2 antibody kinase Syk antibody KSYK antibody KSYK_HUMAN antibody p72-Syk antibody p72syk antibody Spleen tyrosine kinase antibody Syk antibody Tyrosine protein kinase SYK antibody Tyrosine-protein kinase SYK antibody
Function :
Tyrosine-protein kinase SYK, also known as spleen tyrosine kinase, is an enzyme which in humans is encoded by the SYK gene.2-(5-Bromopyridin-2-yl)propan-2-amine uses SYK, along with ZAP70, is a member of the Syk family of tyrosine kinases.98386-83-5 Formula These cytoplasmic non-receptor tyrosine kinases share a characteristic dual SH2 domain separated by a linker domain. However, activation of SYK relies less on phosphorylation by Src family kinases than ZAP70. SYK and ZAP70 share a common evolutionary origin and split from a common ancestor in the jawed vertebrates. While Syk and ZAP70 are primarily expressed in hematopoietic tissues, a variety of tissues express Syk.PMID:33491578 Within B and T cells, respectively, Syk and ZAP70 transmit signals from the B-cell receptor and T-cell receptor. Syk plays a similar role in transmitting signals from a variety of cell surface receptors including CD74, Fc receptor, and integrins.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within human aa 451-500 / 635.
Species reactivity:
Human
Verify application:
WB, IF-Cell
Coupling :
unconjugated
Clone number:
PSH0-76
RRID:
AB_3072610
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 72 kDa
Positive control :
Raji cell lysate, Daudi cell lysate, SW620 cell lysate, Ramos cell lysate, Raji.